目的研究穿琥宁氯化钠注射液对细菌内毒素检查试验的干扰情况,建立穿琥宁氯化钠注射液细菌内毒素检测方法。方法参照《中国药典》2005年版(二部)附录收载的细菌内毒素检查法及其应用指导原则进行试验。结果穿琥宁氯化钠注射液在1:12的稀释倍数下无干扰作用。结论采用细菌内毒素检查法检查穿琥宁氯化钠注射液细菌内毒素是可行的。 Objective To study the interference of permanganate sodium chloride injection on bacterial endotoxin test, and establish a method for detecting bacterial endotoxin in permanganate sodium chloride injection. Methods The bacterial endotoxin test method and its application guidelines, as contained in the appendix of the 2005 edition of the Chinese Pharmacopoeia (Part 2), were used for testing. Results Chlorhexidine sodium chloride injection did not interfere with the 1:12 dilution. Conclusion It is feasible to use bacterial endotoxin test to detect bacterial endotoxin in chlorhexidine chloride injection.