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慢性幽门螺杆菌(Hp)感染已证实是胃癌发生的一个重要危险因素。以往的研究仅限于血清流行病学资料分析,可能低估了Hp感染在胃癌发生中的危险性。为此,作者对胃癌相关胃炎的组织学类型进行了研究,并调查了早期胃癌患者Hp感染者与无症状Hp感染者的关系,进一步了解Hp感染与胃癌的关系。 研究对象为德国不同地区1990年2月至1995年11月接受全胃或部分胃切除的215例早期(pT_1期)胃
Chronic Helicobacter pylori (Hp) infection has proved to be an important risk factor for gastric cancer. Previous studies were limited to sero-epidemiological data analysis and may underestimate the risk of Hp infection in gastric cancer. To this end, the authors studied the histological types of gastric cancer-associated gastritis, and investigated the relationship between Hp infection in asymptomatic patients with asymptomatic Hp infection and further understanding of the relationship between Hp infection and gastric cancer. The subjects were 215 early (pT_1) stomachs receiving total or partial gastrectomy from February 1990 to November 1995 in different regions of Germany.