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目的 探讨功能性消化不良 (FD)的发病机制及普瑞博思对FD的胃动力作用。方法 应用WDL 2 0 0 0型胃动力诊断仪对 12 6例FD患者进行胃动力检测并与 3 0例健康人作对照 ,同时亦比较了服用普瑞博思治疗 4周前后的胃动力改变。结果 显示FD患者中的胃动力低下率为 6 6 7%与健康对照组 10 %相比差异有非常显著性 (P <0 0 1) ,普瑞博思治疗后胃动力恢复正常率为 72 1% ,与治疗前相比具有显著性意义 (P <0 0 5 )。结论 胃动力异常在FD发病中具有重要作用。普瑞博思能有效改善胃动力功能。
Objective To investigate the pathogenesis of functional dyspepsia (FD) and the gastric motility of Prednisol on FD. Methods The gastric motility of 126 patients with FD was measured by WDL 2000 gastric motility diagnostic system and compared with 30 normal controls. The changes of gastric motility before and after 4 weeks of treatment were also compared. The results showed that the gastric motility in the FD patients was 66.7%, which was significantly lower than that in the healthy controls (P <0.01), and the normal rate of gastric motility recovery was 72.1% , Which was significantly higher than that before treatment (P <0.05). Conclusion Abnormal gastric motility plays an important role in the pathogenesis of FD. Puri Booz can effectively improve gastric motility function.