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目的:分析临床药师对临床不合理用药的药学干预。方法:选取500份未进行干预的医嘱,作为未干预组,选取2015年1月~2016年1月期间我院临床药师对临床不合理用药进行药学干预的医嘱500份,作为干预组,对两组医嘱中不合理医嘱、重复给药、不合理用药、抗菌药滥用、无适应症给药进行分析比较,后期追踪相应患者的住院时间、抗菌药费用、药物费用、不良反应发生情况和服药依从性,并进行比较。结果:进行药学干预后,重复给药、不合理用药、无适应症给药的情况得到了显著的减少和控制,总不合理用药的概率由干预前的66.0%降为接受干预的23.6%,同时患者的医疗费用有所减少且病程缩短,患者的不良反应发生情况和服药依从性也比进行干预前的状况好,上述比较结果均差异显著,具有统计学意义(P<0.05)。讨论:临床药师对临床不合理用药进行药学干预能显著降低临床这种现象的发生,规范临床用药,提高临床疗效,以此保证医疗的质量和安全。
OBJECTIVE: To analyze the pharmacological interventions of clinical pharmacists in clinical irrational drug use. Methods: 500 doctors who did not intervene were selected as the non-intervention group, and 500 doctors’ orders of clinical pharmacists in our hospital from January 2015 to January 2016 were selected for the pharmaceutical intervention in clinical unreasonable drugs.As the intervention group, Group doctor’s advice in unreasonable doctor’s advice, repeated administration, irrational medication, abuse of antibiotics, non-indications for analysis and comparison, follow-up of the corresponding patient hospital stay, antibacterial drug costs, drug costs, adverse reactions and medication compliance Sex, and compare. Results: After the intervention, there was a significant decrease and control of repeated medication, irrational medication and no medication. The total irrational medication use rate dropped from 66.0% before intervention to 23.6% after intervention, At the same time, patients ’medical costs decreased and the duration of disease shortened. Patients’ adverse reactions and medication compliance were also better than those before intervention. The above results were significant and statistically significant (P <0.05). Discussion: Clinical pharmacists for clinical irrational drug use for pharmaceutical intervention can significantly reduce the clinical occurrence of this phenomenon, regulate clinical medication, improve clinical efficacy, in order to ensure the quality and safety of medical care.