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目的:探讨格列美脲联合二甲双胍治疗体重超重的2型糖尿病患者的临床疗效。方法:选取我院在2009年10月到2013年01月收治的46例体重超重的2型糖尿病患者随机分为对照组和观察组,对照组患者单独使用格列美脲治疗,观察组患者使用格列美脲联合二甲双胍治疗。结果:观察组临床疗效的总有效率为95.7%,对照组临床疗效的总有效率为78.3%,两组在临床疗效上存在显著差异性(P<0.05);两组患者在临床观察指标上存在显著差异性(P<0.05)。结论:格列美脲联合二甲双胍治疗体重超重的2型糖尿病疗效显著。
Objective: To investigate the clinical efficacy of glimepiride combined with metformin in overweight patients with type 2 diabetes. Methods: Forty-six patients with overweight type 2 diabetes admitted to our hospital from October 2009 to January 2013 were randomly divided into control group and observation group. Patients in control group were treated with glimepiride alone and those in observation group were used Glimepiride combined with metformin treatment. Results: The total effective rate was 95.7% in the observation group and 78.3% in the control group. There was significant difference in clinical efficacy between the two groups (P <0.05) There was significant difference (P <0.05). Conclusion: Glimepiride and metformin are effective in treating overweight type 2 diabetes mellitus.