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癌基因存在于正常的卵巢和睾丸中，在卵巢的生卵、睾丸的生精过程及两者的内分泌功能中均起重要作用。促性腺激素、甾体激素和多种生长因子对性腺功能的调控可能与癌基因的表达有关。
Oncogenes are found in normal ovaries and testes and play an important role in ovarian ovulation, testicular spermatogenesis and both endocrine functions. The regulation of gonadal function by gonadotropins, steroids and various growth factors may be related to the expression of oncogenes.