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目的观察早期应用高压氧治疗急性一氧化碳中毒的疗效,及其对迟发性脑病的预防。方法治疗组选择内蒙古医学院第一附属医院2004—2010年资料较完整、尽早采用高压氧治疗患者96例,对照组为2004年以前未经高压氧治疗患者132例,2组在治疗上除高压氧不同外,其他治疗:如大量持续吸氧、降颅压、保护脑细胞、活血化瘀改善微循环等均相同。结果治疗组在昏迷时间及迟发性脑病的发生上显著低于对照组,2组比较,差异有统计学意义(P<0.05)。结论早期应用高压氧治疗急性一氧化碳中毒疗效好,并能降低其迟发性脑病的发生。
Objective To observe the curative effect of early application of hyperbaric oxygen on acute carbon monoxide poisoning and its prevention on delayed encephalopathy. Methods The treatment group selection First Affiliated Hospital of Inner Mongolia Medical College from 2004 to 2010 more complete data, the early use of hyperbaric oxygen treatment in 96 patients, the control group before 2004 without hyperbaric oxygen therapy in 132 patients, two groups in the treatment of high pressure Oxygen is different, the other treatment: such as a large number of continuous oxygen, reducing intracranial pressure, protecting brain cells, promoting blood circulation to improve microcirculation are the same. Results The incidence of coma and delayed encephalopathy in the treatment group was significantly lower than that in the control group. There was significant difference between the two groups (P <0.05). Conclusions The early use of hyperbaric oxygen in the treatment of acute carbon monoxide poisoning is effective and can reduce the incidence of delayed encephalopathy.