论文部分内容阅读
目的分析左乙拉西坦治疗癫伴认知功能障碍患儿的临床疗效。方法选择在本院接受治疗的癫伴认知功能障碍患儿作为研究对象,分别给予常规治疗及左乙拉西坦治疗,比较2组患儿的认知功能、脑电活动情况及生活质量评分等差异。结果观察组总有效率(66.67%)、MMES评分(25.47±4.83)、无认知功能障碍(83.33%)、躯体功能(76.87±7.16)、心理功能(59.32±5.34)、社会功能(58.76±2.16)、总体生活质量(82.34±8.21)评分均明显高于对照组(P<0.05);癫样放电(15%)、α波(18.21±3.36)、β波(10.32±2.25)、δ(12.36±2.25)、θ波(20.32±3.24)数目均明显少于对照组(P<0.05)。结论左乙拉西坦可有效改善癫伴认知功能障碍患儿的认知功能,减少异常脑电活动,提高生活质量。
Objective To analyze the clinical efficacy of levetiracetam in the treatment of epileptic children with cognitive impairment. Methods The children with epilepsy and cognitive impairment who were treated in our hospital were selected as the treatment group and treated with levetiracetam respectively. The cognitive function, EEG activity and quality of life were compared between the two groups Rating and other differences. Results The total effective rate (66.67%), MMES score (25.47 ± 4.83), no cognitive impairment (83.33%), somatic function (76.87 ± 7.16), mental function (59.32 ± 5.34), social function 2.16), and the overall quality of life (82.34 ± 8.21) were significantly higher than those of the control group (P <0.05). The incidences of epileptiform discharges (15%), α wave (18.21 ± 3.36), β wave (10.32 ± 2.25) (12.36 ± 2.25), θ wave (20.32 ± 3.24) were significantly less than the control group (P <0.05). Conclusion Levetiracetam can effectively improve the cognitive function of children with epilepsy with cognitive impairment, reduce abnormal EEG activity and improve the quality of life.