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目的了解岑溪市水汶镇少年儿童甲型肝炎抗体水平,为制定预防控制策略提供科学依据。方法于2008年12月在岑溪市水汶镇采集2~18岁少年儿童血清样本进行抗-HAV检测。结果共检测2 203人,抗-HAV阳性543例,抗-HAV流行率为24.65%。男、女性阳性率分别为23.56%(269/1 142)、25.82%(274/1 061)。不同年龄组少年儿童血清抗-HAV阳性率差异有统计学意义(P<0.01),7~11岁年龄组阳性率最高(38.90%),12~18岁年龄组阳性率最低(12.97%)。结论岑溪市少年儿童的抗-HAV水平较低,甲肝暴发或流行的潜在风险较大,建议对18岁以下少年儿童开展甲肝疫苗接种,以提高人群抗-HAV水平。
Objective To understand the level of hepatitis A antibody in children and adolescents in Shuiwen Town, Cenxi City, and to provide a scientific basis for the development of prevention and control strategies. Methods Serum samples from 2 to 18 years old children were collected for anti-HAV detection in Shuiben Town, Cenxi City in December 2008. Results A total of 2 203 people were tested, 543 were positive for anti-HAV, and the prevalence of anti-HAV was 24.65%. The positive rates of male and female were 23.56% (269/1 142) and 25.82% (274/1 061) respectively. The positive rates of serum anti-HAV in children of different age groups were statistically significant (P <0.01). The highest positive rate was 38.90% in the age group of 7 to 11 years old and the lowest was 12.97% in the age group of 12 to 18 years old. Conclusion There is a low potential of anti-HAV among children and adolescents in Cenxi City, and the potential risk of hepatitis A outbreak or epidemic is high. Hepatitis A vaccination is recommended for children and adolescents under 18 years of age to increase anti-HAV level in the population.