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许多世纪以来,人们一直认为肺是一些空的气囊,随着空气而膨胀和压缩。最近研究,使人对肺有了另一种认识,似乎可把肺看成为一个巨大腺体,也就是说,肺是具有内分泌功能的器官。在各种病理状态下,肺可以释放一种或多种激素,而肺的激素分泌潜能在肺癌,特别是类癌、燕麦细胞癌患者并发内分泌综合征时,表现得最为突出。非内分泌腺组织来源的肿瘤,产生多肽类激素,临床上产生相应的内分泌综合征者称为“异位性内分泌综合征”。例如,
For many centuries, people have always believed that the lungs are some empty balloons that expand and compress with air. Recent research has given people another understanding of the lungs. It seems that the lung can be seen as a giant gland, that is, the lung is an organ with endocrine function. Under various pathological conditions, the lung can release one or more hormones, and the lung’s hormone secretion potential is most prominent in lung cancer, especially in patients with carcinoid and oat cell carcinoma complicated with endocrine syndrome. Non-endocrine tissue-derived tumors that produce peptide hormones, and those that produce clinically relevant endocrine syndromes, are referred to as “ectopic endocrine syndromes.” E.g,