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目的 分析眼眶原发恶性淋巴瘤的治疗方法。方法 15 例眼眶原发恶性淋巴瘤均为非霍奇金淋巴瘤。 Ann Arbor 分期:Ⅰ A 期11 例,Ⅱ A 期4 例。放射治疗剂量30 ~58 Gy ,3 ~6 周。结果 1 ,3 ,5 年局部控制率分别为94 .1 % ,92 .3 % 和92 .3 % 。3 ,5 ,10 年生存率分别为100 % ,90 % 和75 % 。有5 例疾病进展。结论 放射治疗为主要治疗手段。推荐放射治疗剂量为35 ~45 Gy ,3 .5 ~4 .5 周。不需行淋巴引流区预防照射。对恶性程度高及有眶外侵犯者应加化疗。
Objective To analyze the treatment of orbital primary malignant lymphoma. Methods 15 cases of primary orbital malignant lymphoma were non-Hodgkin’s lymphoma. Ann Arbor staging: Ⅰ A 11 cases, Ⅱ A 4 cases. Radiation therapy dose of 30 ~ 58 Gy, 3 to 6 weeks. The results of 1, 3, 5-year local control rates were 94. 1%, 92. 3% and 92. 3%. The 3-, 5-, 10-year survival rates were 100%, 90% and 75% respectively. There are 5 cases of disease progression. Conclusion Radiation therapy is the main treatment. Recommended dose of radiotherapy 35 ~ 45 Gy, 3. 5 ~ 4. 5 weeks. Do not need lymphatic drainage area to prevent irradiation. On the high degree of malignancy and orbital invasion should be added chemotherapy.