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目的分析心力衰竭患者C-反应蛋白(CRP)、肌钙蛋白Ⅰ(c Tn-Ⅰ)、糖类抗原CA125等指标联合检测的价值。方法选择2012年1月~2015年1月我院收治的心力衰竭患者70例做为观察组,其中心功能Ⅱ级24例、Ⅲ级27例、Ⅳ级19例,选择同期在我院进行体检的健康人群30例做为对照组,两组均体检CRP、c Tn-Ⅰ、CA125等检测指标,对检测结果进行统计分析。结果观察组患者CRP、c Tn-Ⅰ、CA125等指标水平均明显高于对照组(P<0.05);观察组心功能Ⅲ级、Ⅳ级患者CRP、c Tn-Ⅰ、CA125等指标与心功能Ⅱ级患者比较,差异有统计学意义(P<0.05)。结论 CRP、c Tn-Ⅰ、CA125等指标与心力衰竭有密切关系,对心力衰竭的临床诊断、病情判断及预后具有重要的价值。
Objective To analyze the value of combined detection of C-reactive protein (CRP), troponin Ⅰ (cTn-Ⅰ) and carbohydrate antigen CA125 in patients with heart failure. Methods Seventy patients with heart failure treated in our hospital from January 2012 to January 2015 were selected as the observation group, whose central function was grade Ⅱ in 24 cases, grade Ⅲ in 27 cases and grade Ⅳ in 19 cases. During the same period, 30 healthy people as the control group, the two groups were physical examination CRP, cTn-Ⅰ, CA125 and other indicators, the test results were statistically analyzed. Results The levels of CRP, cTn-Ⅰ and CA125 in the observation group were significantly higher than those in the control group (P <0.05). The indexes of CRP, cTn-Ⅰ, CA125 and heart function Ⅱ grade patients, the difference was statistically significant (P <0.05). Conclusion CRP, cTn-Ⅰ, CA125 and other indicators are closely related to heart failure, which is of great value in the clinical diagnosis, diagnosis and prognosis of heart failure.