通过对医院6个品种1210批自制输液,以家兔法(RT法)与鲎试剂法(LT法)进行热原检查比较试验,结果表明:97％以上供试品可通过LT法检查;两法相符率为98.3％;LT法灵敏度高、重复性好、准确可靠,以LT法取代6种输液制剂传统RT法热原检查是可行的。本试验亦提示了标准品内毒素及鲎试剂的质量标化与RT法用于复检所存在的问题。 Through the homemade infusion of 1210 batches of 6 varieties in the hospital, the pyrogen test was compared with the rabbit method (RT method) and the 鲎 reagent method (LT method). The results showed that more than 97% of the samples were tested by LT method; The law coincidence rate was 98.3%. LT method had high sensitivity, good repeatability, accurate and reliable, and it was feasible to replace the 6 kinds of transfusion preparations with traditional RT method pyrogen test by LT method. The test also prompts the quality standardization of standard endotoxin and limulus reagents and RT method for the re-examination of the existing problems.