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我们在体外观察人肺腺癌侵袭时发现,肿瘤细胞表面结构具有多样化和极性化特征,微绒毛、泡状突起和叶状伪足分布于肿瘤细胞顶部,丝状伪足及粗大伪足分布于侧面,其末端抓附于靶器官上。丝状伪足具有粘附、支持、吞噬以及辅助大的伪足运动等功能。粗大伪足起探路和运动作用。肿瘤细胞胞体通过丝状伪足与靶器官保持一定的间距,这种状态可能便于其启动和运动,正在侵袭的细胞表面结构减少。肿瘤细胞各表面结构的比例和变化因靶器官而异,即受基质影响,这种影响具有种属性,而两个细胞系间未见明显差异。
We observed in vitro invasion of human lung adenocarcinoma found that the surface structure of tumor cells with diversified and polarized characteristics, microvilli, vesicles and leafy pseudopodia distributed in the top of the tumor cells, filopodia and coarse pseudopodia Distributed on the side, the end attached to the target organ. Filigree pseudopods with adhesion, support, phagocytosis and assist in large pseudo-foot exercise and other functions. Coarse Pseudo-foot path exploration and exercise. Tumor cells The cell body through the filopodia and the target organ to maintain a certain distance, this state may facilitate its activation and movement, is the invasion of the cell surface structure decreased. The proportions and changes of the surface structures of tumor cells vary with target organs, that is, affected by the matrix. This effect has a species nature, but no significant difference between the two cell lines.