细针穿刺眼内活检(fine-needle aspiration biopsy,FNAB)是眼内肿瘤诊断性活检的重要方法,常用于脉络膜肿瘤以及原发性眼内淋巴瘤的诊断。随着穿刺技术以及标本处理方法的改进,FNAB的诊断敏感性和特异性逐渐增加。与其他眼内活检方法相比,FNAB具有方便、快捷、安全的优点,但肿瘤的播散依然是其潜在的风险。临床应用FNAB需严格掌握其适应证。 Fine-needle aspiration biopsy (FNAB) is an important method for diagnostic biopsy of intraocular tumors and is commonly used in the diagnosis of choroidal tumors and primary intraocular lymphoma. With the improvement of puncture technique and specimen handling, the diagnostic sensitivity and specificity of FNAB gradually increase. Compared with other methods of intraocular biopsy, FNAB has the advantages of convenience, speed and safety, but the spread of tumor is still its potential risk. Clinical application FNAB need to strictly control their indications.