精原干细胞(SSCs)是雄性生殖系干细胞,能自我增殖和减数分裂,形成精母细胞,最终形成精子细胞,向下一代传递遗传信息,是生殖系中唯一在成年之后还能增殖的细胞。将可育供体的SSCs移植到受体睾丸中,可使供体SSCs的生精能力在受体睾丸中恢复,将供体基因型通过受体传给子代。SSCs移 Spermatogonial stem cells (SSCs) are male germline stem cells that proliferate and meiosis themselves to form spermatocytes that eventually form spermatids that transmit genetic information to the next generation, the only cells in the germline that proliferate after adulthood . Transplantation of fertile donor SSCs into the testis can restore the spermatogenic capacity of the donor SSCs in the testes of the recipient and pass the donor genotype through the recipient to the offspring. SSCs shift