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目的观察自体骨髓间充质干细胞转化神经干细胞移植对急性播散性脑脊髓炎后下肢瘫痪的治疗效果。方法采集自体骨髓分离间充质干细胞体外培养增殖后诱导为神经干细胞后移植给患儿。结果患儿下肢的功能明显恢复。结论自体骨髓间充质干细胞转化神经干细胞移植是急性播散性脑脊髓炎后下肢瘫痪的有效方法。
Objective To observe the therapeutic effect of autologous bone marrow mesenchymal stem cells transformed neural stem cell transplantation on paraplegia of lower limbs after acute disseminated encephalomyelitis. Methods Mesenchymal stem cells (MSCs) isolated from autologous bone marrow were collected and proliferated in vitro and then transplanted into NSCs. Results The function of lower limbs of children recovered obviously. Conclusion Transplantation of autologous bone marrow mesenchymal stem cells into neural stem cells is an effective method for the paralysis of lower limbs after acute disseminated encephalomyelitis.