引言 Nielsen和Sillesen于1975年总结了新生婴儿中以常规染色体技术进行的7个细胞遗传学调查的结果。在这7个调查中,用显带染色方法去鉴别怀疑可能是异常的染色体,在所汇总的54,749个新生婴儿中,用常规技术检查染色体异常的频率为6.03‰。 70年代初期出现的染色体显带技术及其 Introduction Nielsen and Sillesen, in 1975, summarized the results of seven cytogenetic studies using conventional chromosomal techniques in newborn infants. In these seven surveys, banding staining was used to identify suspected chromosomal abnormalities. Of the 54,749 newborn babies collected, chromosomal abnormalities were examined by conventional techniques at a frequency of 6.03 ‰. Chromosome Banding Technique in the Early 1970s and Its Application