论文部分内容阅读
目的观察碳酸镧对维持性血液透析患者并继发性甲旁亢的高磷血症的影响。方法将31例血清全段甲状旁腺素(iPTH)300-500pg/ml的维持性血液透析患者随机分为2组,每组均口服骨化三醇1.0ug,2次/周冲击治疗。观察组给予口服碳酸镧咀嚼片(Fosrenol)500mg,3次/d,14例。对照组给予醋酸钙片667mg,3次/d,17例。结果治疗8周后观察组血磷及iPTH较治疗前明显下降,血磷较对照组有明显下降,差异有统计学意义(P<0.05)。结论碳酸镧可有效降低MHD患者并继发性甲旁亢用骨化三醇冲击治疗时的血磷水平。
Objective To observe the effect of lanthanum carbonate on hyperphosphatemia in patients with maintenance hemodialysis and secondary hyperparathyroidism. Methods Thirty-one patients with maintenance hemodialysis with 300-500 pg / ml iPTH (iPTH) were randomly divided into two groups. Each group received oral calcitriol 1.0ug twice a week. The observation group was given oral Fosrenol 500mg, 3 times / d, 14 cases. Control group given calcium acetate tablets 667mg, 3 times / d, 17 cases. Results After 8 weeks of treatment, the levels of phosphorus and iPTH in the observation group decreased significantly compared with those before treatment, and the levels of serum phosphorus in the observation group decreased significantly (P <0.05). Conclusion Lanthanum carbonate can effectively reduce the level of serum phosphorus in patients with MHD and secondary hyperparathyroidism with calcitriol treatment.