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目的:对金双岐片联合美沙拉嗪片治疗溃疡性结肠炎的临床效果进行探讨。方法:选择2012年7月~2014年2月之间我院收治的溃疡性结肠炎患者100例,将其随机均分为两组。对照组采用美沙拉嗪片进行治疗,观察组采用金双岐片联合美沙拉嗪片进行治疗,比较两组患者的临床疗效与治疗前后的IL-8水平变化。结果:经过治疗,两组患者的IL-8水平均得到降低,与治疗前相比差异显著;治疗后,观察组患者的IL-8水平明显低于对照组,差异显著,P<0.05,具有统计学意义;对照组患者的总有效率为68.0%,观察组患者的总有效率为94.0%,远大于对照组。结论:治疗溃疡性结肠炎时,采用金双岐片联合美沙拉嗪片的方式能获得理想的临床效果,可提高治愈率,值得推广。
Objective: To explore the clinical effect of Jin Shuang Qi tablets combined with Mesalazine tablets in the treatment of ulcerative colitis. Methods: One hundred patients with ulcerative colitis admitted to our hospital from July 2012 to February 2014 were randomly divided into two groups. The control group was treated with Mesalazine tablets. The observation group was treated with Jin Shuangqi tablets combined with Mesalazine tablets. The clinical efficacy and IL-8 levels before and after treatment were compared between the two groups. Results: After treatment, the levels of IL-8 in both groups were decreased, which were significantly different from those before treatment. After treatment, the levels of IL-8 in the observation group were significantly lower than those in the control group (P <0.05) The total effective rate in the control group was 68.0%, and the total effective rate in the observation group was 94.0%, much higher than that of the control group. Conclusion: In the treatment of ulcerative colitis, the combination of Jin Shuangqi tablets and Mesalazine tablets can achieve the desired clinical results, which can improve the cure rate and is worth popularizing.