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[目的]探讨年轻子宫内膜癌患者发生卵巢转移的危险因素。[方法]回顾性分析2000年1月至2011年12月住院的年龄≤45岁的85例子宫内膜癌患者的临床病理资料。[结果]85例年轻子宫内膜癌患者中,7例发生卵巢转移。卵巢转移发生率为8.23%(7/85)。单因素分析显示,年轻子宫内膜癌患者发生卵巢转移的危险因素为肿瘤大体类型、子宫肌层浸润、脉管瘤栓、输卵管转移和阴道受侵(P均<0.05)。[结论]保留卵巢能提高年轻子宫内膜癌患者的生活质量。年轻子宫内膜癌患者在进行彻底手术病理分期,确定无卵巢隐性转移及卵巢转移高危因素后,可以选择保留卵巢,并应对保留卵巢患者严密随访。
[Objective] To explore the risk factors of ovarian metastasis in young patients with endometrial cancer. [Methods] The clinical and pathological data of 85 patients with endometrial cancer aged ≤45 years who were hospitalized from January 2000 to December 2011 were retrospectively analyzed. [Results] Among 85 cases of young endometrial cancer, 7 cases had ovarian metastasis. The incidence of ovarian metastasis was 8.23% (7/85). Univariate analysis showed that the risk factors of ovarian metastasis in young patients with endometrial cancer were gross tumor type, myometrial invasion, vascular tumor thrombus, tubal metastasis and vaginal invasion (all P <0.05). [Conclusion] Retained ovary can improve the quality of life of young patients with endometrial cancer. Young patients with endometrial cancer in a thorough surgical pathology staging to determine the risk of ovarian recessive metastasis and ovarian metastasis, you can choose to keep the ovary, and should be closely followed by patients with retained ovary.