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目的:分析变应性鼻炎(AR)患者血清变应原检测结果,了解临床常见的变态反应性疾病特异性变应原及血清总IgE水平变化,探讨总IgE水平对诊断疾病的意义。方法:采用敏筛变应原检测系统对134例AR患者血清变应原及总IgE水平进行检测。结果:134例AR患者中,体外测试变应原阳性患者92例,检出率68.7%,吸入性变应原以户尘螨/粉尘螨最高,阳性率为90%;其次为动物毛皮屑组合/真菌组合,阳性率分别为16%和9%。72例血清总IgE阳性,阳性率为54%。血清总IgE100~200kU/L者21例,占29.2%,其中7例变应原特异性IgE(sIgE)为阴性;血清总IgE>200kU/L者51例,占70.8%,其中4例变应原sIgE为阴性。结论:血清总IgE和变应原sIgE检查,可寻找相应变应原,为AR的预防、诊断及治疗提供重要依据。
OBJECTIVE: To analyze the serum allergen test results in patients with allergic rhinitis (AR) and to find out the clinical common allergic disease-specific allergens and serum total IgE levels and to explore the significance of total IgE levels in the diagnosis of the disease. Methods: Serum allergen and total IgE levels were measured in 134 AR patients by using the sensitive screening allergen detection system. Results: Among the 134 patients with AR, 92 cases were tested positive for allergen in vitro, the detection rate was 68.7%. The inhalation allergen was the highest with 90% of house dust mite and dust mite, followed by animal dander combination / Fungus combination, the positive rates were 16% and 9% respectively. 72 cases of serum total IgE positive, the positive rate was 54%. Serum total IgE100 ~ 200kU / L in 21 cases, accounting for 29.2%, of which 7 allergen-specific IgE (sIgE) was negative; serum total IgE> 200kU / L in 51 cases, accounting for 70.8%, of which 4 cases of allergy The original sIgE is negative. Conclusion: The total serum IgE and allergen sIgE examination can find the corresponding allergen, AR prevention, diagnosis and treatment provide an important basis.