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应用外科方法将曼氏血吸虫成虫移入小鼠的肠系膜静脉,观察这些动物对以后抵抗尾蚴攻击的作用。作者以感染曼氏血吸虫的雌性 HA(ICR)和 CD-1(ICR)小鼠为供体,以提供转种用的25～38日龄的成虫。雌性45～90日龄的 C_3H/HeJ 和45～90日龄的 CD(ICR)小鼠供作转移成虫及尾蚴攻击实验。在成虫移入后10～50天,用逸出2小时以内的活尾蚴50条或100条接种于小鼠皮肤,进行攻击。尾蚴攻击后30天剖检动物,取肝脏和肠系膜静脉进行检虫。对照组分设2组:一组为“假的”对照组,此组小鼠亦进行麻醉、切
Surgical methods were used to transfer adult Schistosoma mansoni to the mesenteric vein of mice and the effects of these animals on resistance to cercariae challenge were observed. The authors used female HA (ICR) and CD-1 (ICR) mice infected with Schistosoma mansoni as donors to provide adult 25- to 38-day-old adults for transplanting. Female C_3H / HeJ aged 45-90 days and CD (ICR) mice aged 45-90 days were used for the challenge of transfer adult and cercariae. 10 to 50 days after the adult was introduced, 50 or 100 live cercariae escaping within 2 hours were inoculated on the mouse skin to be challenged. 30 days after the cercariae challenge animals autopsy, take the liver and mesenteric vein for pests. The control group was divided into 2 groups: one group was “fake” control group, the mice were also anesthetized, cut