脂联素是一种脂肪组织特异性分泌表达的血浆蛋白,主要在白色脂肪组织中表达,具有增强胰岛素的敏感性、抗炎、抗动脉粥样硬化等多重效应。研究发现肥胖、糖尿病、冠心病患者脂联素水平明显降低,表明脂联素的分泌失调与这些疾病的发生有密切的关系。多囊卵巢综合征(PCOS)是育龄妇女中常见的异质性内分泌疾病,胰岛素抵抗是PCOS病理生理过程中的中心环节,研究PCOS患者体内脂联素水平,分析其与胰岛素抵抗的关系,有利于进一步明确PCOS发病机制,为PCOS的诊断和治疗提供新的方法和途径。 Adiponectin is a kind of adipose tissue-specific secreted plasma protein that is mainly expressed in white adipose tissue and has multiple effects of enhancing insulin sensitivity, anti-inflammation and anti-atherosclerosis. The study found that obesity, diabetes, coronary heart disease patients with adiponectin levels were significantly lower, indicating that the secretion of adiponectin disorders and the occurrence of these diseases are closely related. Polycystic ovary syndrome (PCOS) is a common heterogeneous endocrine disease in women of childbearing age. Insulin resistance is the central link in the pathophysiology of PCOS. To study the relationship between adiponectin and insulin resistance in PCOS patients, Which will help further clarify the pathogenesis of PCOS and provide new methods and approaches for the diagnosis and treatment of PCOS.