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由于术前放疗,颁面部恶性肿瘤切除和一期整复手术,常发生局部并发症。作者研究放疗后手术前日腔粘膜温度和氧分压的变化,分析不同的治疗方案和术后局部并发症的关系,观察颌面部恶性肿瘤62例,都是先作放疗,切除肿瘤时一期修复组织缺损.男58人,女4人,年龄28岁～70岁。都是鳞癌,Ⅱ期12例,Ⅲ期20例,Ⅳ期14例,复发癌16例。术前放疗分3组,第1组21例,每次剂量2 Gy,总局灶剂量45Gy。第2组25例,每次3.6Gy,总量56Gy。第3组16例,集中强化放疗,每次4Gy,总量20Gy,其中2次～3次加热。用肌皮瓣修复缺损39例,用口腔粘膜和软组织瓣修复23例。术前先用电测温计测定手术区口腔粘膜温度;随后用极流测定仪(铂接触电极固定在口腔粘膜上),测定在呼吸空气时和吸氧时(流量6L/min)口腔粘膜的氧分压(PO_2),计算口腔粘膜吸收积集氧的速度和潜力。为进行对照,检查15名37岁～61岁健康人和20例33岁～75岁未作放疗的恶性肿瘤患者.
Because of preoperative radiotherapy, the removal of facial malignancy and the first stage reconstructive surgery, local complications often occur. The authors studied changes in the temperature and oxygen partial pressure of the mucous membranes before surgery on the day before radiotherapy, analyzed the relationship between different treatment options and postoperative local complications, and observed 62 cases of malignant tumors in the maxillofacial region. Repair tissue defect. 58 males and 4 females, aged 28 to 70 years old. All of them were squamous cell carcinomas, 12 in stage II, 20 in stage III, 14 in stage IV, and 16 in recurrence. Preoperative radiotherapy was divided into 3 groups. The first group consisted of 21 patients. Each dose was 2 Gy, and the total focal dose was 45 Gy. The second group of 25 cases, each 3.6Gy, total 56Gy. The third group consisted of 16 patients with concentrated radiation therapy, 4Gy each time, totaling 20 Gy, of which 2 to 3 heating. Thirty-nine patients were repaired with myocutaneous flaps and 23 patients were treated with oral mucosa and soft tissue flaps. Before the operation, the temperature of the oral mucosa of the operation area was measured with an electric thermometer; then, the polar flow meter (the platinum contact electrode was fixed on the oral mucosa) was used to measure the oral mucosa when breathing air and oxygen (flow rate 6 L/min). Oxygen partial pressure (PO 2 ) calculates the speed and potential of oxygen accumulation in the oral mucosa. For comparison, 15 healthy patients aged 37 to 61 years and 20 patients 33 to 75 years old who had not undergone radiotherapy were examined.