急性颅内高压动物模型一般系采用向脑室内定量注入生理盐水或人工脑脊液来形成。但用此法产生的颅内高压压力不稳定,随时间衰减。我们改用恒压灌注的方法形成颅内高压动物模型,方法简单,压力恒定。如果调节恒压灌注器的高度,还可获得准确的不同程度的颅内压。本方法是形成急性颅内高压动物模型较好的方法。 Acute intracranial hypertension animal model generally used intraventricular injection of normal saline or artificial cerebrospinal fluid to form. However, the pressure generated by this method of intracranial hypertension is unstable and decays with time. We use constant pressure perfusion method to form intracranial hypertension animal model, the method is simple, constant pressure. If you adjust the height of the constant pressure syringe, but also to obtain accurate different degrees of intracranial pressure. This method is a good method to form an acute intracranial hypertension animal model.