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目的了解邗江农村全面性强直阵挛发作(GTCS)患者抗癫痫药物治疗状况,为进一步开展农村社区癫痫防治工作提供依据。方法采用随机抽样的方法选取207例GTCS患者进行调查。结果调查的207例患者中接受正规治疗的患者仅68例(32.85%),其中单药治疗21例(30.88%),联合用药47例(69.12%);正规服药患者与未正规服药患者的疗效比较差异有显著性(P<0.001)。结论江苏邗江地区GTCS患者中正规服用抗癫痫药物者比例较小,且单药比例明显偏低,剂量偏小,存在较多的不良反应,患者依从性差,控制情况不理想,管理水平较落后,还存在较大的治疗缺口。
Objective To understand the antiepileptic drug treatment in patients with QHD in rural comprehensive tonic-clonus attack (GTCS) and provide the basis for further prevention and treatment of epilepsy in rural community. Methods A random sample of 207 patients with GTCS were selected for investigation. Results Of the 207 patients surveyed, only 68 patients (32.85%) received formal treatment, of which 21 patients (30.88%) were treated with monotherapy and 47 patients (69.12%) were treated with combination therapy. The efficacy of regular medication and non-formal medication The difference was significant (P <0.001). Conclusions The proportion of patients with GTCS taking regular antiepileptic drugs in Qijiang area of Jiangsu Province is relatively small, the proportion of single drug is obviously low, the dose is small, there are many adverse reactions, the patient compliance is poor, the control situation is not ideal, the management level is backward, There is also a larger treatment gap.