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结节病是一种受累器官以T 淋巴细胞/单核巨噬细胞浸润为主无干酪样变性肉芽肿为特征的疾病.虽然结节病是一种系统性疾病.但激活的T 淋巴细胞和单核巨噬细胞仅在受累的器官出现.结节病性肺泡炎以激活的肺泡巨噬细胞和T 细胞为特点.由巨噬细胞释放的白介素-1(IL-1)和白介素-6(IL-6)在T 细胞的细胞周期中具有重要的作用.作者测定了6例对照组(A组),15例结节病患者,其中活动期10例(B 组),缓解期5例(C 组)的支气管肺泡灌洗细胞(BALC)和周围血单核细胞
Sarcoidosis is a disease characterized by an infiltration of T lymphocytes / monocytes by predominantly caseous non-caseous granulomas.Although sarcoidosis is a systemic disease, activated T lymphocytes and Mononuclear macrophages appear only in affected organs, and sarcoid alveolitis is characterized by activated alveolar macrophages and T cells.Leukin-1 (IL-1) and interleukin-6 IL-6) plays an important role in the cell cycle of T cells.The authors measured 6 cases of control group (group A) and 15 cases of sarcoidosis patients, including 10 cases of active stage (group B), 5 cases of remission C group) of bronchoalveolar lavage cells (BALC) and peripheral blood mononuclear cells