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目的 探讨老年肺癌患者行全肺切除的可行性和预后。方法 自 1 985～ 1 995年 ,我们对2 3例 6 5岁以上非小细胞肺癌 (NSCLC)患者行全肺切除 ,选择同期小于 6 5岁行全肺切除的 99例NSCLC患者作为对照 ,比较两组病例 5年生存率、手术并发症和死亡率、手术前后肺功能的改变。生存率分析采用Kaplan Meier法。结果 老年组 5年生存率与对照组相似 (2 7.5 6 %比 30 .5 1 % ,P >0 .0 5 ) ,但手术并发症和死亡率明显高于对照组 (1 3.0 4%比 2 .0 2 % ,P <0 .0 5 )。结论 全肺切除术对老年NSCLC患者仍然合适 ,但因手术合并症和死亡率较高 ,故应认真选择手术适应证
Objective To investigate the feasibility and prognosis of pneumonitis in elderly patients with lung cancer. METHODS: From 1985 to 1995, we performed pneumonectomy on 23 patients with non-small cell lung cancer (NSCLC) over 65 years of age. We selected 99 NSCLC patients who underwent pneumonectomy at the same time and were used as controls. The 5-year survival rate, surgical complications and mortality, and changes in lung function before and after surgery were recorded in both groups. The Kaplan Meier method was used for survival analysis. Results The 5-year survival rate of the elderly group was similar to that of the control group (27.56% vs. 30.51%, P > 0.05), but the operative complications and mortality were significantly higher than those of the control group (1 3.04% vs 2 .0 2 %, P <0 .0 5 ). Conclusion Pneumonectomy is still suitable for elderly patients with NSCLC, but surgical complications and mortality are high, so the indication should be carefully selected