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目的探讨贝那普利联合阿托伐他汀治疗2型糖尿病并发肾病的临床效果。方法选取我院收治的140例2型糖尿病并发肾病病人为研究对象,以随机信封法分为对照组与联合组各70例,对照组单用贝那普利治疗,联合组在此基础上加用阿托伐他汀,对两组病人临床疗效和不良反应进行观察对比。结果联合组Hb Alc、FPG、u-ALB、β2-MG、Scr均明显低于对照组,P<0.05。结论贝那普利与阿托伐他汀联用可有效降低2型糖尿病并发肾病病人血糖水平,并能改善病人肾功能指标,值得临床推广。
Objective To investigate the clinical effect of benazepril combined with atorvastatin on type 2 diabetic nephropathy. Methods A total of 140 patients with type 2 diabetes mellitus complicated with nephropathy admitted to our hospital were enrolled in this study. They were randomly divided into control group and combination group, 70 cases in each group. The control group was treated with benazepril alone. On the basis of this, With atorvastatin, the clinical efficacy and adverse reactions in both groups were observed and compared. Results The levels of Hb Alc, FPG, u-ALB, β2-MG and Scr in the combined group were significantly lower than those in the control group (P <0.05). Conclusions The combination of benazepril and atorvastatin can effectively reduce the blood glucose level in patients with type 2 diabetes mellitus complicated with nephropathy and can improve the renal function of patients, which is worthy of clinical promotion.