我科自1990年以来,对所有检查确诊的淋病患者(含青霉素治疗无效者)全部试用利福平、氟哌酸、SMZ联合疗法,收到较好效果,现报告如下。54例中,男8例,女46例。病程3～106天。所有患者均有不洁性交史及典型临床表现,分泌物涂片均查见细胞内或细胞内外革兰阴性双球菌。 Our department since 1990, all checked diagnosed gonorrhea patients (including penicillin ineffective treatment) all trial rifampin, norfloxacin, SMZ combination therapy, received good results, are as follows. 54 cases, 8 males and 46 females. Duration of 3 to 106 days. All patients have unclean sex history and typical clinical manifestations, secretions smear were found intracellular or intracellular or extracellular Gram-negative bacteria.