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目的：探讨急性胰腺炎患者早期内镜逆行胰胆管造影（ＥＲＣＰ）及内镜治疗的应用价值及安全性。方法：选择６６例次急性胰腺炎患者作早期（１～７ｄ内）ＥＲＣＰ及内镜治疗（ＥＲＣＰ组），并以同期保守治疗的６０例次急性胰腺炎患者作对照（对照组），观察了两组患者血清淀粉酶恢复时间、腹痛缓解时间、住院天数及并发症发生情况。结果：（１）ＥＲＣＰ组中，３６例次为胆道疾病患者，４例次为胰管结石，４例次为胰腺分裂症，３例次为乳头旁巨大憩室，１９例次ＥＲＣＰ未见异常。（２）３３例次患者作了内镜下治疗，其中内镜下十二指肠乳头括约肌切开术及取石术１７例次，４例次作了副乳头切开及扩张术，１２例次作了鼻胆管引流术。（３）ＥＲＣＰ组腹痛缓解天数及平均住院天数分别为（１１．５±３．６）及（２１．７±５．０）ｄ，明显短于对照组（１５．４±７．８）及（３３．０±６．８）ｄ（Ｐ＜０．０１）。血清淀粉酶恢复时间两组相差不显著。两组均未发生严重并发症。结论：急性胰腺炎患者早期ＥＲＣＰ及内镜治疗是安全、有效的，尤其是对胆源性胰腺炎应尽早行ＥＲＣＰ及内镜治疗
Objective: To investigate the value and safety of early endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic treatment in patients with acute pancreatitis. Methods: Sixty-six patients with acute pancreatitis were enrolled in the ERCP group (ERCP group) at the early stage (within 1 to 7 days). Sixty patients with acute pancreatitis who underwent conservative treatment in the same period were selected as the control group (control group) Two groups of patients with serum amylase recovery time, abdominal pain relief time, hospitalization days and complications. Results: (1) In the ERCP group, 36 cases had biliary disease, 4 cases had pancreatic duct stones, 4 cases had pancreatic schizophrenia, 3 cases had papillary giant diverticulum, and 19 cases had no ERCP. (2) Thirty-three patients underwent endoscopic treatment, including 17 cases of endoscopic duodenal sphincterotomy and stone removal, 4 cases of secondary papilla incision and dilation, 12 cases of secondary Nasobiliary drainage was done. (3) The days of abdominal pain relief and mean hospital stay in ERCP group were (11.5 ± 3.6) and (21.7 ± 5.0) days, respectively, which were significantly shorter than those in control group (15.4 ± 7.8) and (33.0 ± 6.8) d (P <0.01). Serum amylase recovery time was not significantly different between the two groups. No serious complications occurred in either group. Conclusion: Early ERCP and endoscopic treatment of patients with acute pancreatitis is safe and effective, especially ERCP and endoscopic treatment of biliary pancreatitis