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作者报告和分析本院1963～1984年收治的401例的颊粘膜癌的临床和治疗惰况。376例(93.8%)属于鳞状上皮癌,其鳞癌Ⅰ级占68.5%。25例(6.2%)是小涎腺来的腺源性上皮癌。本组病例的治疗以彻底的外科切除术为主,其5年治愈率为42.1%,但有周围结构受累者5年治愈率为26%。预后与患者病损的病理分级和TNM分类有关。对有皮肤受累者必须洞穿彻底切除其皮肤。后颊浸润性病损者,应对其颞下间隙和翼颌间隙内容进行清扫。对于中晚期病例术前化疗可提高疗效。
The authors report and analyze the clinical and therapeutic heterogeneity of 401 cases of buccal mucosal cancer admitted to our hospital from 1963 to 1984. 376 cases (93.8%) belonged to squamous cell carcinoma and their squamous cell carcinoma grade I accounted for 68.5%. Twenty-five patients (6.2%) were adenoid epithelial carcinomas from the small salivary glands. The treatment of this group of patients was based on thorough surgical resection. The 5-year cure rate was 42.1%, but the 5-year cure rate of surrounding structural involvement was 26%. The prognosis is related to the pathological grade of the patient’s lesion and the TNM classification. For those with skin involvement, they must be thoroughly excised to remove their skin. Patients with cheek-infiltrating lesions should be cleared of the infrapatellar space and flap clearance. For early and late cases, preoperative chemotherapy can improve the efficacy.