论文部分内容阅读
本文应用体外培养掺入~3H-TdR的放射自显影术研究慢性萎缩性胃炎(CAG)的细胞动力学特点,并试图以标记指数(LI)为依据进行分级,即根据胃粘膜病情轻重不同按标记指数划分为四级。0级的病理改变为慢性浅表性胃炎,Ⅰ级为轻度CAG,Ⅱ级为中—重度CAG,Ⅲ级为胃癌。这种分级的意义在于从细胞动力学角度正确判断病理改变程度,用以作为CAG病情演变的观察指标,并检出易发生癌的“高危险性”胃粘膜。
In this study, the autophagy of 3H-TdR in vitro was used to study the cellular dynamics of chronic atrophic gastritis (CAG), and it was attempted to use the labeling index (LI) as the basis for classification, that is, according to the severity of gastric mucosal conditions. The labeling index is divided into four levels. The grade 0 pathological changes were chronic superficial gastritis, grade I was mild CAG, grade II was moderate-severe CAG, and grade III was gastric cancer. The significance of this grading lies in the correct judgment of the degree of pathological changes from the perspective of cell dynamics, which is used as an observation index for the evolution of the condition of CAG and the detection of “high-risk” gastric mucosa prone to cancer.