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对 16例糖尿病 (DM)伴视网膜病变及 18例糖尿病不伴视网膜病变的患者进行了内皮素 (ET)、尿微量白蛋白排泄率 (UAER)检测 ,并对 16例正常人进行了ET及UAER检测。结果表明糖尿病病人伴视网膜病变或不伴视网膜病变者ET均较正常人高 ,糖尿病伴视网膜病变组除UAER显著高于无视网膜病变组外 ,ET也明显高于糖尿病无视网膜病变组 ;相关分析表明ET与UAER及视网膜病变程度均呈正相关 ,表明糖尿病合并有微血管病变时 ,ET明显增高。提示ET在反映糖尿病微血管并发症中具有重要意义
Endothelin (ET) and urinary albumin excretion rate (UAER) were measured in 16 patients with diabetic retinopathy and 18 with diabetic retinopathy. ET and UAER were measured in 16 normal subjects Detection. The results showed that patients with diabetic retinopathy or retinopathy with ET were higher than normal, diabetic retinopathy group except UAER was significantly higher than the non-retinopathy group, ET was significantly higher than the diabetic group without retinopathy; correlation analysis showed that ET and UAER and retinopathy were positively correlated, indicating that diabetes mellitus with microvascular lesions, ET was significantly higher. Tip ET in reflecting the microvascular complications of diabetes is of great significance