本文介绍用体外培养的食管癌109细胞株筛选药物的方法,以及用此法筛选60种中草药和8种复合中草药的初步结果。从中观察到对细胞杀伤作用较强的药物有:防己、蛇莓、王不留、番木鳖及冬凌草等。当冬凌草和龙葵联合应用时药物作用明显增强,可为单独应用时的2倍、6倍。本文还讨论了上述中草药临床合理应用的可能性。 This article describes the method of screening drugs with esophageal cancer cell line 109 cultured in vitro, and the preliminary results of screening 60 kinds of Chinese herbal medicines and 8 kinds of compound Chinese herbs by this method. Observed from the cell killing effect of drugs are: Fangji, snakeberry, Wang does not stay, hibiscus and rubescens. When the combination of Rubescens and Solanum nigrum was used, the effect of the drug was significantly enhanced, which could be twice or six times that of the single application. This article also discusses the possibility of clinically rational application of these Chinese herbs.