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目的:探讨前列腺体积(PV)及膀胱出口梗阻(BOO)与前列腺穿刺活检阳性率的关系,从而探讨它们对于早期诊断前列腺癌的价值。方法:选择我院初次行前列腺穿刺活检的男性患者293例为研究对象,在术前进行经直肠超声检查、残余尿、尿流率及血前列腺特异性抗原(PSA)检查,以最大尿流率(Qmax)<10ml/s认为存在膀胱出口梗阻。结果:通过病检结果确认前列腺癌患者90例,非前列腺癌患者203例。根据PV及Qmax分别将患者分组,当PSA为4-10ng/ml时,若合并前列腺增生则穿刺阳性率下降至7.14%;合并BOO则下降至8.45%。结论:前列腺体积及膀胱出口梗阻是前列腺癌的可预测因素,其独立或联合均对指导临床上前列腺穿刺活检具有较高价值,在前列腺癌诊断中具有无创、方便、低风险性等优点。
Objective: To investigate the relationship between prostate volume (PV) and bladder outlet obstruction (BOO) and the positive rate of prostatic biopsy, and to explore their value in the early diagnosis of prostate cancer. Methods: A total of 293 male patients undergoing prostatic biopsy in our hospital were enrolled in this study. Transrectal ultrasonography, residual urine, urinary flow rate and PSA were performed preoperatively. The maximum urinary flow rate (Qmax) <10ml / s that there is bladder outlet obstruction. Results: 90 cases of prostate cancer and 203 cases of non-prostate cancer were confirmed by pathological examination results. According to PV and Qmax, patients were divided into groups. When the PSA was 4-10ng / ml, the positive rate of prostatic hyperplasia decreased to 7.14% and the combined BOO decreased to 8.45%. Conclusions: Prostate volume and bladder outlet obstruction are predictive factors of prostate cancer. Independently or in combination, they have high value in directing clinical prostatic biopsy, and have the advantages of non-invasive, convenient and low-risk in the diagnosis of prostate cancer.