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目的:探讨COOK宫颈扩张球囊在足月妊娠促宫颈成熟引产中的临床效果及安全性。方法:回顾性分析2011年9月至2014年10月广州市花都区妇幼保健院收治的300例足月妊娠有引产指征孕妇的临床资料,根据促宫颈成熟方式的不同分为研究组(COOK宫颈扩张球囊,173例)和对照组(地诺前列酮栓,127例),比较两组促宫颈成熟情况、引产结局、新生儿结局及引产过程差异。结果:置入或用药后两组Bishop评分均较治疗前提高(P<0.05),但两组之间差异无统计学意义(P>0.05)。研究组缩宫素使用率、引产成功率、阴道分娩率高于对照组,产后出血量、剖宫产率低于对照组(P<0.05);两组第一产程时间、宫颈裂伤发生率、阴道血肿率、新生儿体质量、新生儿窒息率、新生儿窘迫率、新生儿第1分钟Apgar评分比较,差异无统计学意义(P>0.05)。结论:COOK宫颈扩张球囊在足月妊娠促宫颈成熟引产中具有较好临床效果,不增加产妇和胎儿并发症,具有安全、有效的特点。
Objective: To investigate the clinical effect and safety of COOK cervical dilatation balloon in induction of cervical ripening in term pregnancy. Methods: The clinical data of 300 full-term pregnant women with induced labor indications for pregnant women who were admitted to Maternal and Child Health Hospital of Huadu District in Guangzhou from September 2011 to October 2014 were retrospectively analyzed. According to the different ways of promoting cervical ripening, the patients were divided into study group ( COOK cervical dilatation balloon, 173 cases) and control group (dinoprostone suppository, 127 cases). The differences of cervical ripening, induction of labor, neonatal outcome and induction of labor were compared between the two groups. Results: The Bishop scores of both groups were significantly higher than those before treatment (P <0.05), but there was no significant difference between the two groups (P> 0.05). The oxytocin use rate, success rate of induced labor and vaginal delivery rate in the study group were higher than those in the control group. The amount of postpartum hemorrhage and cesarean section rate were lower in the study group than in the control group (P <0.05) , Vaginal hematoma rate, neonatal body weight, neonatal asphyxia, neonatal distress rate, neonatal 1 minute Apgar score, the difference was not statistically significant (P> 0.05). Conclusions: COOK cervical dilatation balloon has good clinical effect in inducing cervical ripening in full term pregnancy without increasing maternal and fetal complications, which is safe and effective.