原发性中枢神经系统淋巴瘤(primary central nervous system lymphoma,PCNSL)是一种仅发生于脑和脊髓,而没有全身其他淋巴结或淋巴组织浸润的淋巴瘤,约占颅内肿瘤的1%~2%,在病理确诊前,影像学诊断符合率低,多数被误诊为胶质瘤、转移瘤、脑膜瘤及室管膜瘤等[1]。本研究回顾性分析19例经病理证实的PCNSL的临床和影像学特征,结合文献复习,以提高对该病的认识。 Primary central nervous system lymphoma (PCNSL) is a lymphoma that occurs only in the brain and spinal cord without infiltration of other lymph nodes or lymphoid tissues throughout the body, accounting for 1% to 2% of intracranial tumors %, Before the pathological diagnosis, imaging diagnosis of low coincidence, the majority were misdiagnosed as glioma, metastases, meningioma and ependymoma [1]. This study retrospectively analyzed the clinical and imaging features of 19 PCNSLs confirmed by pathology and reviewed the literature to improve the understanding of the disease.