The title compound 5 was synthesized in 45% yield by the reaction of compound 3 with α, α’-bis (bromomethyl)-2, 2’-bipyridine in CH3CN at 70℃ for 24 h.
Promoted by active indium produced in situ by Sm/InCl3 · 4H2O system, arylidenecyano- acetates undergo reductive cyclodimerization to afford cyclopentamine der