目的比较万乃洛韦和阿昔洛韦治疗生殖器疱疹的疗效。方法生殖器疱疹68例,随机分组。治疗组34例口服万乃洛韦300mg,bid;对照组34例,口服阿昔洛韦200mg,5次/d,疗程均10d。结果万乃洛韦起效时间短于阿昔洛韦(P<0.05),两者疗效相当(P>0.05)。结论万乃洛韦是治疗生殖器疱疹安全、快速、有效的药物。 Objective To compare the efficacy of valacyclovir and acyclovir in the treatment of genital herpes. 68 cases of genital herpes, randomized. In the treatment group, 34 cases were given valacyclovir 300 mg twice daily, while in the control group 34 cases were given acyclovir 200 mg 5 times daily for 10 days. Results Valasoflovir onset time was shorter than acyclovir (P <0.05), both of the efficacy of the two (P> 0.05). Conclusion Valacyclovir is a safe, rapid and effective drug for the treatment of genital herpes.