论文部分内容阅读
目的探讨妊娠期肝内胆汁淤积症(ICP)的临床特点和治疗方法。方法对我院1999年1月至2006年12月共收治的妊娠期肝内胆汁淤积症患者86例的临床资料进行回顾性分析。结果ICP孕妇血清总胆汁酸(STBA)值随孕周增加而逐渐升高;分娩前保肝治疗不能改善患者的肝功能,但结束妊娠后肝功能恢复正常;86例患者中发生早产24例(27.91%),剖宫产术62(72.09%),胎儿窘迫38例(44.18%),无围产儿死亡病例。结论妊娠期肝内胆汁淤积症对母体及胎儿的危害较大,及时终止妊娠是治疗此病的关键。
Objective To investigate the clinical features and treatment of intrahepatic cholestasis of pregnancy (ICP). Methods The clinical data of 86 patients with intrahepatic cholestasis of pregnancy admitted in our hospital from January 1999 to December 2006 were retrospectively analyzed. Results The level of serum total bile acid (STBA) in ICP pregnant women increased gradually with the increase of gestational age. Pre-delivery hepatoprotection did not improve the liver function of patients, but returned to normal after termination of pregnancy. Among 86 patients, 24 27.91%), cesarean section 62 (72.09%), fetal distress 38 cases (44.18%), no cases of perinatal deaths. Conclusion Intrahepatic cholestasis of pregnancy is more harmful to the mother and the fetus. Terminating the pregnancy in time is the key to the treatment of this disease.