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目的对维持性血液透析患者残余肾功能(RRF)进行评价及探究相关的影响因素。方法选取2014年5月至2015年10月于我院行血液透析治疗的患者共83例,评价所有患者的24 h尿量,将24 h尿量>100mL者归为RRF组,24 h尿量<100 mL者归为无残余肾功能组。全部患者均行血液生化检查,指标包括血钙、血磷、血白蛋白、血甲状旁腺激素及血红蛋白,统计各项指标与肾小球滤过率及尿素清除率的相关系数,比较不同组别各项指标的变化情况。结果血磷、血白蛋白、血红蛋白及血甲状旁腺激素均与肾小球滤过率相关;2组间比较显示血磷及血全段甲状旁腺素(iPTH)水平差异有统计学意义(P<0.05)。结论患者的残余肾功能采用24 h尿量进行评价,简单易行;延缓透析患者的残余肾功能的降低对于患者的预后有积极的意义。
Objective To evaluate the residual renal function (RRF) in maintenance hemodialysis patients and explore the influencing factors. Methods A total of 83 patients undergoing hemodialysis in our hospital from May 2014 to October 2015 were enrolled in this study. The 24-hour urine output of all patients was evaluated. The patients with 24-hour urine output> 100mL were classified as RRF group and the 24-hour urine output <100 mL were classified as no residual renal function. All patients underwent biochemical blood tests. The indexes included serum calcium, serum phosphorus, serum albumin, parathyroid hormone and hemoglobin. The correlation coefficients between each index and glomerular filtration rate and urea clearance rate were compared. Do not change the various indicators. Results Serum phosphorus, serum albumin, hemoglobin and parathyroid hormone were correlated with glomerular filtration rate (GFR). The levels of P and PTH in the two groups were significantly different (P < P <0.05). Conclusion The residual renal function in patients with 24 h urine output evaluation, simple and easy; delayed dialysis patients with residual renal function reduction for the prognosis of patients with positive significance.