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目的:了解小儿急性呼吸道感染(acute respiratory tract infection ARTI)中病毒感染状况,为预防和治疗疾病提供依据。方法:收集2009年5月～2010年4月期间340例确诊为ARTI住院患儿的深部鼻咽分泌物(NPS)临床标本,采用逆转录聚合酶链反应(RT-PCR)法检测常见的7种呼吸道病毒:呼吸道合胞病毒(RSV)、流感病毒(IFV)、副流感病毒(PIV)、人类偏肺病毒(HMPV)、腺病毒(ADV)、鼻病毒(HRV)和肠道病毒(EV)。统计分析各种病毒所致ARTI的临床特点及流行特征。结果:340例标本中共检出212例阳性,阳性率为62.35%。其中RSV感染为132例,阳性率为62.3%;IFV感染为45例、阳性率为21.3%;PIV感染为13例,阳性率为6.1%;HMPV感染为13例,阳性率为6.1%;ADV感染为4例,阳性率为1.9%;HRV感染为2例,阳性率为0.9%;EV感染为7例,阳性率为3.3%。结论:本地区诊断为ARTI住院儿童中病毒感染率为62.35%,其中以RSV为主。
Objective: To understand the status of virus infection in children with acute respiratory tract infection (ARTI) and provide basis for prevention and treatment of disease. Methods: A total of 340 clinical samples of deep nasopharyngeal secretions (NPS) from 340 children admitted to hospital for ARTI from May 2009 to April 2010 were collected. Reverse transcriptase-polymerase chain reaction (RT-PCR) Respiratory syncytial virus (RSV), influenza virus (IFV), parainfluenza virus (PIV), human metapneumovirus (HMPV), adenovirus (ADV), rhinovirus (HRV) and enterovirus ). Statistical analysis of various viruses ARTI clinical features and epidemiological characteristics. Results: A total of 212 positive cases were detected in 340 cases, the positive rate was 62.35%. RSV infection in 132 cases, the positive rate was 62.3%; IFV infection in 45 cases, the positive rate was 21.3%; PIV infection in 13 cases, the positive rate was 6.1%; HMPV infection in 13 cases, the positive rate was 6.1%; ADV Infection was 4 cases, the positive rate was 1.9%; HRV infection in 2 cases, the positive rate was 0.9%; EV infection in 7 cases, the positive rate was 3.3%. Conclusion: The prevalence of virus infection in hospitalized children with ARTI is 62.35% in this region, of which RSV is the main factor.