论文部分内容阅读
目的 :通过测定子宫内膜异位症 (EM)患者血清和腹腔液中铁离子浓度是否较正常人升高来了解其与EM的关系及其在引起不孕机制中的作用。方法 :EM患者 48例及对照组 15例的血清和腹腔液 ,运用铬天青S的方法测定铁离子浓度。结果 :血清和腹腔液中铁离子浓度在EM患者Ⅲ～Ⅳ期中较Ⅰ～Ⅱ期及对照组明显升高 ,且两者间呈正相关 ;在EM各期曾受孕与不孕组间无明显差异。结论 :EM患者病情严重程度与血清和腹腔液中铁离子浓度高低呈正相关 ,在临床工作中可通过测定血清中铁离子浓度来进行粗略分期 ,从而有利于治疗方法的选择 ,简便易行。EM中铁离子与不孕间无明显因果关系。
OBJECTIVE: To determine whether iron concentration in serum and peritoneal fluid in patients with endometriosis (EM) is elevated or not and to investigate its relationship with EM and its role in causing infertility. Methods: Serum and peritoneal fluid from 48 patients with EM and 15 patients from the control group were assayed for iron ion concentration by the method of chrome azure S. Results: The concentration of iron in serum and peritoneal fluid was significantly higher in patients with stage Ⅲ ~ Ⅳ of EM than those in stage Ⅰ ~ Ⅱ and the control group, and there was a positive correlation between them. There was no significant difference between the two groups in the stage of pregnancy and infertility. Conclusion: The severity of EM patients is positively correlated with the concentration of iron ion in serum and peritoneal fluid. In clinic, the staging of iron ion concentration in serum can be used to facilitate the choice of treatment method, which is simple and easy to operate. There is no obvious causal relationship between iron ions and infertility in EM.