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目的:采用EuroQol五维调查问卷表(EQ-5D)对2型糖尿病患者健康相关的生活质量进行评价,并分析其主要影响因素,探讨健康状况发展与生活质量下降的关系。方法:采用EQ-5D问卷及访问,对南京大学附属南京鼓楼医院内分泌门诊256例2型糖尿病患者生活质量和健康状况进行研究。结果:全体患者EQ-5D分值平均0.790±0.158。理想控制的患者组平均值0.836(0.810～0.861; 95%CI),良好控制和控制差的组的分值分别相当于理想患者的92.2%、84.8%。出现一种或多种并发症的患者分值0.692(0.667～0.717;95%CI),未出现并发症的患者提高到0.863(0.842～0.88 3; 95%CI)。各种并发症的发生发展与血糖控制情况对生活质量影响程度最强。结论:EQ-5D量表适用于中国2型糖尿病患者健康状况测量,适宜成本-效果分析研究。血糖控制不理想和各并发症的发生发展是患者生活质量下降的主要影响因素。
OBJECTIVE: To evaluate the health-related quality of life of type 2 diabetic patients using EuroQol five-dimensional questionnaire (EQ-5D) and to analyze the main influencing factors and to explore the relationship between the development of health status and the decline of quality of life. Methods: Using EQ-5D questionnaire and interview, the quality of life and health status of 256 type 2 diabetic patients in endocrinology clinic of Nanjing Drum Tower Hospital, Nanjing University were studied. Results: The EQ-5D scores of all patients average 0.790 ± 0.158. The mean score for the optimally controlled group was 0.836 (0.810-0.861; 95% CI). The scores for the well-controlled and poorly-controlled groups were 92.2% and 84.8% of the ideal, respectively. Patients with one or more of these complications had a score of 0.692 (0.667-0.717; 95% CI) and patients without complications increased to 0.863 (0.842-0.883; 95% CI). The occurrence and development of various complications and glycemic control have the strongest impact on quality of life. Conclusion: The EQ-5D scale is suitable for measuring the health status of type 2 diabetic patients in China and is suitable for cost-effectiveness analysis. Poor blood glucose control and the occurrence and development of complications are the main factors affecting the quality of life of patients.