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尖端扭转型室速(TdP)是一种伴有Q-T间期延长的多形性室速,可发生于好多临床情况,但最常见由药物引起.非镇静H_1受体拮抗剂如苄苯派咪唑(astemizole)和丁苯哌丁醇(terfenadine)亦可引起此类心律失常.本文报告1例可能为先天性散发性Q-T间期延长服用治疗量丁苯哌丁醇导致尖端扭转型室速.患者女性,42岁,反复昏厥发作2天共3次,于1992年8月入院.当昏劂发作时无抽搐表现,无大小便失禁,意识恢复迅速不留后遗症.患者在4个月之前因易怒于1992年4月入院检查,当时ECG示Q-T_c间期延长(577和567ms),血钾3.5-4.0mml/L(正常值3.5-5.5mmol/L)、血钙2.2mmol,/L(正常值2.1—2.6mmol/L)、血镁0.8mmol/L(正常值0.7-1.15mmol/L,否认既往有心脏疾患、昏厥、心悸、呼吸急促或胸
TdP, a pleomorphic VT with prolongation of the QT interval, can occur in a wide range of clinical situations, but is most commonly caused by drugs. Non-sedating H 1 -receptor antagonists such as benzylbenzimidazole (astemizole) and terfenadine can also cause this type of arrhythmia.This article reports a possible congenital sporadic QT prolonging the dose of buformin-induced torsades de pointes caused by ventricular tachycardia patients Female, 42 years old, recurrent seizures 2 days a total of 3 times, admitted to hospital in August 1992. No convulsions when fainting performance, no incontinence, rapid recovery of consciousness without leaving sequelae. 4 months ago due to patients Fury was admitted to hospital in April 1992, when the ECG showed Q-T_c interval prolongation (577 and 567 ms), potassium 3.5-4.0 mml / L (normal 3.5-5.5 mmol / L), calcium 2.2 mmol / L (Normal 2.1-2.6mmol / L), blood magnesium 0.8mmol / L (normal 0.7-1.15mmol / L, denied the previous heart disease, fainting, palpitations, shortness of breath or chest