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目的 探讨妊娠合并先天性心脏病手术后对妊娠结局的影响。方法 回顾性分析50例妊娠合并先天性心脏病患者的临床资料。结果 ①妊娠合并先天性心脏病患者以房间隔缺损和室间隔缺损为主,占48.0%(24/50)。②手术组与未手术组比较,心功能Ⅲ～Ⅳ级与肺动脉高压的发生率降低(P<0.05);3例心力衰竭均发生在未手术组,死亡1例;手术组无早产与围产儿死亡,而未手术组早产4例(26.7%),1例死亡。③妊娠合并先天性心脏病分娩方式以剖宫产为主(72.0%),手术组与未手术组比较,差异无统计学意义(P>0.05)。结论 妊娠合并先天性心脏病确诊后宜尽早手术治疗,术后可降低母儿的发病率及死亡率;剖宫产终止妊娠是比较安全的分娩方式。
Objective To investigate the effect of gestational pregnancy outcome after pregnancy complicated with congenital heart disease. Methods Retrospective analysis of 50 cases of pregnancy with congenital heart disease in patients with clinical data. Results ① The patients with congenital heart disease complicated by atrial septal defect and ventricular septal defect accounted for 48.0% (24/50). ②The incidences of Ⅲ ~ Ⅳ and pulmonary hypertension were significantly lower in the operation group than in the non-operation group (P <0.05); 3 cases of heart failure occurred in the non-operation group and 1 died; in the operation group, there were no preterm and perinatal 4 cases (26.7%) were premature, and 1 died. ③ cesarean section was the main mode of delivery of pregnancy complicated with congenital heart disease (72.0%), there was no significant difference between operation group and non-operation group (P> 0.05). Conclusion Pregnancy complicated with congenital heart disease should be diagnosed as soon as possible after surgery, postoperative morbidity and mortality can be reduced maternal; cesarean termination of pregnancy is a relatively safe mode of delivery.