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整肠生是应用二十多年的地衣芽胞杆菌活菌制剂,已有大量的研究报道其临床有效性和安全性。地衣芽胞杆菌大量分泌种类丰富的消化酶,通过抑制肠道有害菌生长和促进有益菌增殖调节肠道菌群,并产生杆菌肽、地衣素和乙酸等生物活性物质发挥益生作用。本文总结了益生菌的益生特点,并重点分析了芽胞杆菌的益生特点,归纳了整肠生的作用机制与临床研究现状,揭示了其在肝脏疾病、溃疡性结肠炎、肠易激综合征、幽门螺旋杆菌感染以及病毒感染等疾病中的治疗作用,并对整肠生未来的临床应用方向进行了展望。
Intestinal intestine is the application of Bacillus licheniformis for more than 20 years of preparation, a large number of studies have reported its clinical efficacy and safety. Bacillus licheniformis secretes a great variety of digestive enzymes in large quantities, which regulate the gut flora by inhibiting the growth of harmful bacteria in the gut and promoting the proliferation of beneficial bacteria, and producing bioactive substances such as bacitracin, lichenin and acetic acid to exert probiotic effects. This article summarizes the probiotic characteristics of probiotics, and analyzes the probiotic characteristics of Bacillus, summarizes the mechanism of action and clinical research status of probiotics, reveals its disease in the liver, ulcerative colitis, irritable bowel syndrome, Helicobacter pylori infection and viral infection in the treatment of diseases, and the clinical application of the future direction of the whole intestine is prospected.