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目的:观察海洋溶菌酶膜剂(商品名:海妇洁膜)治疗细菌性阴道病的疗效。方法:将收治的细菌性阴道病患者,经微生物学检查未合并其他阴道炎者300例,随机分为两组,研究组150例,用海妇洁膜治疗,对照组150例,用甲硝唑泡藤片治疗。观察并比较两组治疗结束后3天的有效率和不良反应,于下次月经干净后复查各组的复发率。结果:研究组有效率为96%,对照组为78%,复查复发率:研究组为8.03%,对照组20.93%,两组比较,差别有显著性意义(P<0.01)。另外,研究组未出现不良反应,对照组有36例(24.00%)患者在用药期间有阴道烧灼感,41例(27.33%)患者反映阴道分泌物多。结论:海妇洁膜治疗细菌性阴道病疗效肯定,复发率低,安全性高。
Objective: To observe the efficacy of marine lysozyme film (trade name: sea-woman film) in the treatment of bacterial vaginosis. Methods: 300 patients with bacterial vaginosis who were treated by microbiological examination without other vaginitis were randomly divided into two groups, 150 cases in study group, treated with sea-fog film and control group with 150 cases. Riboflavin tablets treatment. Observed and compared three days after the end of the two groups were effective and adverse reactions, the next menstrual cycle after the review of the recurrence rate of each group. Results: The effective rate was 96% in the study group and 78% in the control group. The recurrence rate was 8.03% in the study group and 20.93% in the control group. There was significant difference between the two groups (P <0.01). In addition, the study group did not appear adverse reactions, 36 patients (24.00%) in the control group had vaginal burning sensation during the medication, 41 patients (27.33%) patients reflect more vaginal discharge. Conclusions: The treatment of bacterial vaginosis with seafloor clean film has certain efficacy, low recurrence rate and high safety.